Five‐year follow‐up study of hyperechogenicity of the substantia nigra in Parkinson's disease
Identifieur interne : 003916 ( Main/Exploration ); précédent : 003915; suivant : 003917Five‐year follow‐up study of hyperechogenicity of the substantia nigra in Parkinson's disease
Auteurs : Daniela Berg [Allemagne] ; Berthold Merz [Allemagne] ; Karlheinz Reiners [Allemagne] ; Markus Naumann [Allemagne] ; Georg Becker [Allemagne]Source :
- Movement Disorders [ 0885-3185 ] ; 2005-03.
English descriptors
- KwdEn :
- MESH :
- ultrasonography : Parkinson Disease, Substantia Nigra.
- Adult, Aged, Female, Follow-Up Studies, Humans, Male, Middle Aged, Severity of Illness Index.
Abstract
Using transcranial sonography, an area of hyperechogenicity at the substantia nigra (SN) may be detected as a typical marker in patients with Parkinson's disease (PD) as well as in approximately 9% of healthy subjects vulnerable to nigrostriatal impairment. In this longitudinal study, we provide evidence that the area of SN hyperechogenicity does not change in the course of PD. In conjunction with earlier findings in children and adolescents, this evidence indicates that, from late adolescence onward, this ultrasound finding is a trait marker for nigrostriatal vulnerability. © 2004 Movement Disorder Society
Url:
DOI: 10.1002/mds.20311
Affiliations:
- Allemagne
- Bade-Wurtemberg, Bavière, District de Basse-Franconie, District de Tübingen
- Tübingen, Wurtzbourg
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In this longitudinal study, we provide evidence that the area of SN hyperechogenicity does not change in the course of PD. In conjunction with earlier findings in children and adolescents, this evidence indicates that, from late adolescence onward, this ultrasound finding is a trait marker for nigrostriatal vulnerability. © 2004 Movement Disorder Society</div></front></TEI><affiliations><list><country><li>Allemagne</li></country><region><li>Bade-Wurtemberg</li><li>Bavière</li><li>District de Basse-Franconie</li><li>District de Tübingen</li></region><settlement><li>Tübingen</li><li>Wurtzbourg</li></settlement></list><tree><country name="Allemagne"><region name="Bade-Wurtemberg"><name sortKey="Berg, Daniela" sort="Berg, Daniela" uniqKey="Berg D" first="Daniela" last="Berg">Daniela Berg</name></region><name sortKey="Becker, Georg" sort="Becker, Georg" uniqKey="Becker G" first="Georg" last="Becker">Georg Becker</name><name sortKey="Berg, Daniela" sort="Berg, Daniela" uniqKey="Berg D" first="Daniela" last="Berg">Daniela Berg</name><name sortKey="Merz, Berthold" sort="Merz, Berthold" uniqKey="Merz B" first="Berthold" last="Merz">Berthold Merz</name><name sortKey="Naumann, Markus" sort="Naumann, Markus" uniqKey="Naumann M" first="Markus" last="Naumann">Markus Naumann</name><name sortKey="Reiners, Karlheinz" sort="Reiners, Karlheinz" uniqKey="Reiners K" first="Karlheinz" last="Reiners">Karlheinz Reiners</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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